The Houston Astros (81-68) and San Diego Padres (85-65) meet on Monday and start a 3-game set. First pitch from Petco Park is scheduled for 9:40 p.m. ET. Let’s check out BetMGM Sportsbook’s MLB odds around the Astros vs Padres Opportunities and place your best bets with our expert MLB tips and predictions.

Season series: First meeting; Houston won 2-1 in 2023

Houston continues its road tour that began with the club winning a 3-game series against the Los Angeles Angels Friday through Sunday. Overall, the Astros have won 4 games in a row and 11 of their last 17 games.

The Padres are back home after a 4-1 road trip. That short road trip ended with the Friars winning 3 of 3 games against the San Francisco Giants over the weekend.

Expected Astros starters at the Padres

RHP Spencer Arrighetti against RHP Yu Darvish

Arrighetti (7-12, 4.72 ERA) is making his 27th start. He has a WHIP of 1.42, 4.2 BB/9 and 10.8 K/9 in 131 2/3 IP.

• Last appearance: No decision, 6 2/3 IP, 2 ER, 7 H, 1 BB, 7 K in 4-3 home loss to Oakland A’s on Tuesday
• Held opposing batters to .679 OPS and posted a 3.31 ERA in the second half of the season
• Has never played against the Padres

Darvish (5-3, 3.52 ERA) is scheduled to make his 14th start. He has a WHIP of 1.14, 2.4 BB/9 and 8.7 K/9 in 64 IP.

• Last appearance: Win, 5 IP, 2 ER, 7 H, 0 BB, 5 K in the 7-3 win at the Seattle Mariners on Tuesday
• Career vs. Astros (regular season): 5-5, 3.64 ERA (94 IP, 38 ER), 1.09 WHIP, 11.8 K/9 in 15 starts
• Third start since returning from the injured list (elbow) on September 4

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Astros vs Padres odds

Provided by BetMGM Sportsbook; visit the USA TODAY Sports Scores and Sports Betting Odds Hub for a complete list of MLB odds. Odds last updated at 10:50 a.m. ET.

• Money line: Astros +105 (bet $100 to win $105) | Padres -125 (bet $125 to win $100)
• Run Line (RL)/Against the Spread (ATS): Astros +1.5 (-210) | Padres -1.5 (+170)
• Over/Under (O/U): 8 (O: -105 | U: -115)

Tips and predictions for the Astros at the Padres

forecast

Astros 4, Padres 3

Money line

HOUSTON (+105) has a record of 14-4 in their last 18 games against the NL West.

The Astros have inexplicably gone just 15-26 in one-run games and 5-10 in extra-inning games. They have underperformed their 4.63 runs per game and 4.00 RPG and are likely to be weak in the next few games.

That tendency is broken in this mound matchup. Arrighetti has been pretty good. He looks like a 27-year-old who is getting a handle on things, and he has a decent 3.06 ERA in his last 6 road starts. His rest interval also fits the bill as a green check. Arrighetti has struggled on long rest and 4-day rest. His 5-day interval (which applies to this start) is 3.58 ERA with 3.3 K/BB.

San Diego has only won 5-6 of their last 11 home games. ASTROS (+105) as a game of values.

Running Line/Against the Spread

HAPPEN to bring the full juice into play with this RL offer.

Over/Under

The under has conceded in 6 of Houston’s last 9 games and in 11 of the club’s last 16 away games.

Arrighetti’s forecast puts some downward pressure on this one. Add to that a cool evening and two big-league bullpens. TAKE THE UNDER 8 (-115).

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