The Oakland A’s (63-82) and Houston Astros (77-67) play the middle game of a 3-game series on Wednesday. First pitch from Minute Maid Park is scheduled for 8:10 p.m. ET. Let’s check out FanDuel Sportsbook’s odds around the A’s vs Astros Opportunities and place your best bets with our expert MLB tips and predictions.

Season series: Astros lead 7-4

Oakland took a 4-3 win as a moderate underdog (+176) behind LHP JP Sears in the series opener on Tuesday, when Under (8.5) was connected.

The A’s have been out of the postseason race for some time now, but Oakland hasn’t raised the white flag. In fact, the A’s have a winning record of 8-7 in their last 15 games since August 25. The Over has won in 8 of their last 12 games.

The Astros are still in 1st place in the AL West, but they have struggled over the last 7 games, going 2-5 since September 2nd while the Overs have scored in 3 of the previous 4 games.

Expected starters for the A’s and the Astros

RHP Joey Estes against RHP Hunter brown

Estes (6-7, 4.46 ERA) makes his 21st start and 22nd appearance. He has a 1.13 WHIP, 1.9 BB/9 and 7.0 K/9 in 111 IP (1 CG).

• Last start: Loss, 4 IP, 4 ER, 6 H, 0 BB, 3 K in 6-4 home loss to Seattle Mariners on Thursday
• 2024 Road Splits: 2-5, 6.66 ERA, 48 2/3 IP, 36 ER, 10 HR, 1.48 WHIP, .286 opposing batting average (OBA), 15 BB, 43 K in 10 starts (11 appearances)
• Career against the Astros: Loss, 3 2/3 IP, 8 ER, 8 H (1 HR), 4 BB, 4 K in 8-1 road loss on May 16 in only career start against Houston

Brown (11-7, 3.41 ERA) is making his 28th start and 29th appearance. He has a 1.27 WHIP, 3.2 BB/9 and 9.5 K/9 in 153 IP.

• Last start: No decision, 6 IP, 0 ER, 4 H, 1 BB, 6 K in 1-0 road loss to Cincinnati Reds on Thursday
• 2024 Home Splits: 5-3, 3.12 ERA, 75 IP, 26 ER, 10 HR, 1.15 WHIP, .212 OBA, 29 BB, 74 K in 13 starts
• Career vs. A’s: 3-0, 1.80 ERA (30 IP, 6 ER), 2 HR, 0.97 WHIP, 11.4 K/9 in 5 starts

Who goes yard? Here is a breakdown of today’s best home run props with our top picks. These include the BetMGM Bonus Code SBWIRE receives an offer of $1,500 for his first bet.

A’s at Astros odds

Provided by FanDuel Sportsbook; for a complete list visit the USA TODAY sports scores and betting odds hub. Odds last updated at 3:35 a.m. ET.

• Moneyline (ML): A’s +190 (bet $100 to win $190) | Astros -230 (bet $230 to win $100)
• Running Line (RL)/Against the Spread (ATS): A’s +1.5 (-114) | Astros -1.5 (-105)
• Over/Under (O/U): 8.5 (O: +100 | U: -122)

Tips and predictions for the A’s at the Astros

forecast

Astros 6, A’s 3

Money line

The Astros (-230) will cost you well over twice your potential winnings, and that’s too risky for a single bet. Even as part of a multi-stakes parlay, including Houston will suck up the entire value of your ticket.

Additionally, Houston hasn’t been dominant lately, winning just twice in their last seven games.

However, the A’s (+190) are a risky proposition only because Estes has been a complete disaster on the road.

HAPPEN.

Running Line/Against the Spread

Back ASTROS -1.5 (-105) by nearly 1-1 to set the run line. While Houston has only 9 wins in its last 20 games since August 20, it won by 2 or more runs in 8 of those wins. So if you want the Astros to win, you’d want them to clean up on the run line.

Over/Under

OVER 8.5 (+100) it is worth playing lightly with even-money, but go with a Half-unit game maximum.

The over is 6-4 in Estes’ last 10 starts, and he has posted a dismal 6.66 ERA in 48 2/3 IP in 10 starts and 1 relief appearance on the road this season.

The Astros have a 3-1 over in their last 4 games, while Brown has been successful in 2 of their last 3. Bet big, but be careful.

Play our free daily Pick’em Challenge and win! Play Now!

More tips and recommendations for sports bettingcheck out SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X And like us on Facebook.

Fantasy Baseball Help from BaseballHQ.com:
Subscribe now to dominate the competition.