The No. 21 Clemson Tigers and NC State Wolfpack open ACC play Saturday afternoon when the two teams meet at Memorial Stadium in Clemson, SC. ​​After a season-opening loss to No. 1 Georgia, the Tigers (1-1) bounced back two weeks ago with a 66-20 win over Appalachian State. They are coming off an off week. Meanwhile, the Wolfpack (2-1) enter Saturday’s game after a 30-20 win over Louisiana Tech last week.

Kickoff is at 12:00 p.m. ET. The Tigers are 18-point favorites according to the latest Clemson vs. NC State odds, while the over/under limit for total points is 44. (For current odds for every game this week, visit our college football odds page.)

Before you make any picks or predictions on the NC State vs. Clemson college football game, you MUST check out the predictions from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its launch, it has returned over $2,000 on $100 bettors with its top-rated college football picks against the spread. It also has a profitable season going 13-9 on top-rated spread picks and started this season 5-2 on over/under picks. Everyone who has followed it has seen strong returns.

The model knows that the Tigers have dominated the head-to-head series against NC State recently. Clemson has won nine of the last 11 games in the series and 16 of the last 19. The Tigers also have a 27-11 record at home against the Wolfpack.

But the model also takes into account that NC State has a receiver with a feel for the end zone in KC Concepcion. The 6’1″, 195-pound sophomore from Charlotte has caught 13 touchdowns since the start of last season, ranking second in the country, only Arizona’s Tetairoa McMillan (14) is better. This season, Concepcion has already caught three touchdowns, ranking 13th in the country.

For Saturday, the model has Clemson vs. NC State in its sights. We can tell you that it is over the total, predicting a total of 47 points, and it also says In almost 70% of the simulations, one side of the spread is correct. You MUST watch it before you make your college football picks.

Who wins NC State Comparisons Clemson? And which side of the spread is accurate in nearly 70% of simulations? … Join SportsLine now to find out which side of the Clemson vs. NC State spread you should bet on Saturday using the model that’s winning college football picks!