The Pittsburgh Pirates (74-85) and the New York Yankees (93-66) begin a three-game interleague series on Friday at Yankee Stadium. First pitch is scheduled for 7:05 p.m. ET (MLB Network/ESPN+). Let’s analyze BetMGM Sportsbook’s 24/7 MLB odds Pirates vs. Yankees Opportunities and meet our expert MLB picks and predictions for the best bets.

Season Series: First Meeting; The Yankees went 2-1 in 2023

The Pirates have lost two of three games against the Milwaukee Brewers from Tuesday to Thursday, and Pittsburgh has lost four straight series, going 4-9 in its last 13 games since losing a three-game set against Sept. 9-11 the Miami Marlins won.

The under has cashed in 4 of the last 5 games for the Bucs while going 9-3 in the last 12 games. In interleague play, Pittsburgh has gone 7-2 in their last 9 attempts.

For the Yankees, they have secured the AL East Division title and are just one game ahead of the Cleveland Guardians for the top spot in the AL playoffs this weekend.

New York went 10-1 on Thursday to clinch the AL East and is 10-4 since Sept. 11. The score is 4-0-1 in the last five games. The Yankees are just 3-5 in their last eight games against the NL, while the Over have come into the money in their last five interleague games at home.

Pirates at Yankees scheduled starters

RHP Jared Jones vs LHP Carlos Rodon

Jones (6-8, 4.14 ERA) is making his 22nd career start. He has a WHIP of 1.18, 2.8 BB/9 and 9.6 K/9 in 117 1/3 IP.

• Last start: Loss, 5 IP, 6 ER, 6 H (2 HR), 3 BB, 5 K in a 7-1 road setback to the Cincinnati Reds last Saturday
• 2024 career/road split: 2-5, 5.96 ERA, 48 1/3 IP, 32 ER, 46 H, 10 HR, 13 BB, 52 K, .250 opponent batting average (OBA), 1.22 WHIP in 9 starts
• Last 7 games: 2-2, 4.93 ERA, 38 1/3 IP, 21 ER, 34 H, 15 BB, 40 K, 1.28 WHIP
• Never played against the Yankees

Rodon (16-9, 3.98 ERA) is making his 32nd start. He has a WHIP of 1.21, 2.8 BB/9 and 10.1 K/9 in 169 2/3 IP.

• Last start: Win, 6 IP, 0 ER, 5 H, 1 BB, 4 K in a 10-0 road win over Oakland Athletics last Saturday
• 2024 home division: 9-2, 3.09 ERA, 75 2/3 IP, 26 ER, 13 HR, 23 BB, 86 K, .202 OBA, 1.06 WHIP in 13 starts
• Last 7 games: 3-2, 3.29 ERA, 38 1/3 IP, 14 ER, 10 BB, 47 K, 1.20 WHIP
• Career vs. Pirates: 3-2, 3.99 ERA, 29 1/3 IP, 13 ER, 3 HR, 4 BB, 33 K, 1.09 WHIP in 5 starts

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Pirates to Yankees victory

Powered by BetMGM Sportsbook; Visit the USA TODAY sports scores and sports betting hub for a complete list of MLB odds. Lines were last updated at 6:17 a.m. ET.

• Moneyline (ML): Pirates +150 (bet $100 to win $150) | Yankees -185 (bet $185 to win $100)
• Run Line (RL)/Against the Spread (ATS): Pirates +1.5 (-130) | Yankees -1.5 (+110)
• Over/Under (O/U): 8 (O: -115 | U: -105)

Pirates at Yankees tips and predictions

forecast

Yankees 6, Pirates 3

Money line

The Yankees (-185) are a bit too expensive for a single bet, costing you almost twice your potential return. However, it is perfectly fine to use the Bronx Bombers as part of a multi-stage parlay.

For a single bet HAPPEN, and look at the running line instead.

Running Line/Against the Spread

Back the YANKEES -1.5 (+110) with plus money it’s one and a half runs.

While the Pirates +1.5 (-130) have a respectable 23-23 record against left-handed starters, it’s Jones who can’t be trusted. He was phenomenal at home in his first season in the majors, but he was a disaster away from home. He has a 2-5 record with a 5.96 ERA and the Bronx Bombers will likely send him into the offseason with another L.

Over/Under

OVER 8 (-115) is the lean, but go with a Half-unit game.

The Yankees are 4-0-1 in their last five games, while they are 12-4 in their last 16 interleague contests at The Stadium.

For the Bucs, the over has scored in just one of the last five games. However, the total has been high for Jones in four of the last five road starts.

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