WOODLAND HILLS, Calif. – Rams head coach Sean McVay said Monday that injuries suffered by wide receiver Cooper Kupp (ankle), safety John Johnson III (shoulder) and offensive lineman Jonah Jackson (shoulder) in Week 2 against the Cardinals will keep those three players out of action for an “extended period of time.”

McVay clarified that Kupp’s ankle injury was a sprain, while Jackson re-injured his shoulder injury from the previous season in the third quarter of yesterday’s game and continued playing despite it.

Although none of the trio’s injuries are season-ending, McVay says all are candidates for Injured Reserve (IR).

“We’re running out of spots and we’re only in Week 3 as far as returning to play,” McVay said, referring to the NFL rule that allows teams to bring back up to eight players from the injured list during the regular season. “But that’s a possibility for all of those guys.”

McVay also said kicker Joshua Karty has a “mild groin injury that will keep him out of practice for the next few days,” but Karty should be good to go for Sunday’s Week 3 game against the 49ers.

Kupp’s injury follows Puka Nacua, who was placed on the injured list last week after spraining his posterior cruciate ligament in the season opener against the Lions. McVay had previously said Nacua could miss more than the minimum four games. Kupp had 18 catches for 147 yards and 1 touchdown before suffering his ankle injury in the first half of last Sunday’s game against the Cardinals.

Because of Jackson’s injury, the Rams will have their third starting left guard of the season heading into Sunday’s Week 3 game against the 49ers. Jackson moved from center to the position after Steve Avila sprained his medial collateral ligament (MCL) against the Lions; Avila was subsequently placed on the injured list last week.